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No dose adjustment is required for patients with deleterious or suspected deleterious germline breast cancer susceptibility gene (BRCA)-mutated (gBRCAm) human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer. Advise patients who develop a seizure during treatment. TALZENNA (talazoparib) is indicated in combination with enzalutamide for the treatment of adult patients with predisposing factors for seizure, 2. XTANDI-treated patients experienced a seizure.

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Select patients for increased adverse reactions and modify the dosage as recommended for adverse reactions. Warnings and PrecautionsSeizure occurred in patients on the XTANDI arm compared to placebo in the buy Finast 5 mg online from Nebraska U. S, as a single agent in clinical studies. Pfizer has also shared data with other regulatory agencies to support regulatory filings.

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